This literature study aims to examine the existence of cancer stem cells in Breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, Breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the Breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic Breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive Breast cancer patients.

Background: Breast cancer is one of the most common cancer diseases among women worldwide. Breast cancer brings fear into many womens? life. It is a threat against life, but also to the psychological health, self-esteem and the female identity. Aim: The aim of this literature review was to describe newly Breast cancer patient?s perception of information provided by healthcare personnel.

Body image in women with breastcancerBreast cancer is the second most common form of cancer in Sweden today. To get a Breast cancer diagnose can be a traumatic experience for many women. It´s difficult to forsee how these women are going to control their situation. When a breast has to be removed because of cancer, the women has to adjust to changes in both physical and phychological aspects. The aim of this study was to elucidate body image in women with Breast cancer after a mastectomy.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, Breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the Breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic Breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive Breast cancer patients.

Background                      There are different types of treatments for Breast cancer, and these may be of surgical and non-surgical art. These treatments produce different side effects that can cause both physical and mental harm to the woman. The Breast cancer can change the women's body image and relationships to their families. The women manage their lives in different ways depending on which culture they belong to. Aim                                    The aim of the study was to elucidate women?s experience of her body and the altered body in relation to Breast cancer treatment.Method                              The method used was a literature review based on scientifically articles to overview the field of Breast cancer.

Introduction: Breast pain, mastalgia, is a common problem for many women. The pain can cause so much concern that the woman seeks help in health care. The cause of concern is often that that the pain may be due to Breast cancer. Women with mastalgia are referred for mammography to investigate the cause of the pain. Experience says that the mammography is mostly normal.Aim: The aim of the study was to get an overall picture of the results of the mammograms performed on Mammography SU / Sahlgrenska in 2011.

Background: Breast cancer is one of the most common types of cancer in the world and it usually affects elderly women. However, there are between 600-700 cases per year in Sweden where women under the age of 45 are diagnosed. Removal of the breast or part of the breast, hair loss, fatigue and nausea as a result of the Breast cancer treatment has an emotional and physical impact on the women?s lifeworld. The nurse should build a relationship with the women to identify and meet their needs. Aim: To describe younger women?s experiences of getting a Breast cancer diagnosis and life afterwards.Method: Four biographical books were analyzed to match the aim of the study.Result: The findings were that the women experience similar thoughts and feelings when it comes to living with a cancer diagnosis.

Breast cancer is the most common form of cancer affecting women. The treatment of Breast cancer may lead to forcing the woman to remove her breast. The breast is a symbol of femininity and sexuality for many women. The purpose of this literature-based study is to describe women's experiences of altered body image and sexuality after mastectomy. This may provide a better understanding of the nurse in responding to these Breast cancer patients.

Background: Breast cancer is one of the most common cancer diseases among women worldwide. Breast cancer brings fear into many womens? life. It is a threat against life, but also to the psychological health, self-esteem and the female identity. Aim: The aim of this literature review was to describe newly Breast cancer patient?s perception of information provided by healthcare personnel.

The most common form of female cancer in Sweden is Breast cancer and the primary choice of treatment is surgery. Removing a woman's breasts is not just removing a body part but is also strongly linked to the emotional life. This has psychosocial consequences and the reactions will be different depending on how people perceive health and illness. Factors that matter are both personal experiences and cultural factors such as religion, family, and the own standards and values. It is important that a nurse is aware of cultural factors that may influence the perception of care.

Breast cancer is the most common form of cancer which struck women around the world. When a human is exposed to threat or stress, e.g. Breast cancer, different coping strategies are used in order to cope with the situation by the afflicted person. The aim of this literature study was to describe how women, who suffered from Breast cancer, experienced coping with their situation. Scientific articles were found in the databases Medline (Pub Med) and Cinahl.

Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly Breast cancer and ovarian cancer.

Background: In Sweden around 6500 women suffer each year from Breast cancer and during lifetime every tenth women is affected. Mastectomy (removal of part of or the whole breast) is carried out mostly in purpose to remove malign tumours or in prophylactic purpose. The breast can be rebuilt through breast reconstruction. Method: The result analysis was based on nine articles. A Manifest content analysis was used and data from the articles where divided into themes and patterns, on the basis of these categories were created.

AbstractAim: The aim of this study was to describe which coping strategies women use when they have been diagnosed with Breast cancer. In addition, the purpose was to describe how woman?s self-image changes after a mastectomy. Method: A literature review study has been carried out with a descriptive design. The result of the study included 16 articles which were found in the databases: Cinahl, PubMed, PsycInfo and through manual search.